Infection of human retinal pigment epithelial cells with influenza A viruses.
Identifieur interne : 001086 ( Main/Exploration ); précédent : 001085; suivant : 001087Infection of human retinal pigment epithelial cells with influenza A viruses.
Auteurs : Martin Michaelis [Allemagne] ; Janina Geiler ; Denise Klassert ; Hans Wilhelm Doerr ; Jindrich CinatlSource :
- Investigative ophthalmology & visual science [ 1552-5783 ] ; 2009.
Descripteurs français
- KwdFr :
- ARN messager (métabolisme), Antiviraux (pharmacologie), Apoptose, Caspase-3 (métabolisme), Cellules cultivées, Chimiokines (métabolisme), Effet cytopathogène viral, Humains, Interféron de type I (pharmacologie), Interféron gamma (pharmacologie), RT-PCR, Relation dose-effet des médicaments, Ribavirine (pharmacologie), Réplication virale (), Réplication virale (physiologie), Sous-type H1N1 du virus de la grippe A (physiologie), Sous-type H2N2 du virus de la grippe A (physiologie), Sous-type H5N1 du virus de la grippe A (physiologie), Épithélium pigmentaire de la rétine (anatomopathologie), Épithélium pigmentaire de la rétine (virologie).
- MESH :
- anatomopathologie : Épithélium pigmentaire de la rétine.
- métabolisme : ARN messager, Caspase-3, Chimiokines.
- pharmacologie : Antiviraux, Interféron de type I, Interféron gamma, Ribavirine.
- physiologie : Réplication virale, Sous-type H1N1 du virus de la grippe A, Sous-type H2N2 du virus de la grippe A, Sous-type H5N1 du virus de la grippe A.
- virologie : Épithélium pigmentaire de la rétine.
- Apoptose, Cellules cultivées, Effet cytopathogène viral, Humains, RT-PCR, Relation dose-effet des médicaments, Réplication virale.
English descriptors
- KwdEn :
- Antiviral Agents (pharmacology), Apoptosis, Caspase 3 (metabolism), Cells, Cultured, Chemokines (metabolism), Cytopathogenic Effect, Viral, Dose-Response Relationship, Drug, Humans, Influenza A Virus, H1N1 Subtype (physiology), Influenza A Virus, H2N2 Subtype (physiology), Influenza A Virus, H5N1 Subtype (physiology), Interferon Type I (pharmacology), Interferon-gamma (pharmacology), RNA, Messenger (metabolism), Retinal Pigment Epithelium (pathology), Retinal Pigment Epithelium (virology), Reverse Transcriptase Polymerase Chain Reaction, Ribavirin (pharmacology), Virus Replication (drug effects), Virus Replication (physiology).
- MESH :
- chemical , metabolism : Caspase 3, Chemokines, RNA, Messenger.
- chemical , pharmacology : Antiviral Agents, Interferon Type I, Interferon-gamma, Ribavirin.
- drug effects : Virus Replication.
- pathology : Retinal Pigment Epithelium.
- physiology : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H2N2 Subtype, Influenza A Virus, H5N1 Subtype, Virus Replication.
- virology : Retinal Pigment Epithelium.
- Apoptosis, Cells, Cultured, Cytopathogenic Effect, Viral, Dose-Response Relationship, Drug, Humans, Reverse Transcriptase Polymerase Chain Reaction.
Abstract
Ocular involvement in influenza A virus diseases is common but usually limited to mild conjunctivitis. Rarely, inflammation of the choriocapillaris may result in atrophia of the retinal pigment epithelium (RPE). Primary human retinal pigment epithelial (RPE) cells were infected with seasonal (H1N1 A/New Caledonia/20/99, H3N2 A/California/7/2004) or highly pathogenic avian H5N1 (A/Thailand/1(Kan-1)/04, A/Vietnam/1203/04, A/Vietnam/1194/04) influenza strains.
DOI: 10.1167/iovs.09-3752
PubMed: 19553611
Affiliations:
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Le document en format XML
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Goethe-Universität, Frankfurt-am-Main</wicri:regionArea><wicri:noRegion>Frankfurt-am-Main</wicri:noRegion><wicri:noRegion>Frankfurt-am-Main</wicri:noRegion><wicri:noRegion>Frankfurt-am-Main</wicri:noRegion></affiliation></author><author><name sortKey="Geiler, Janina" sort="Geiler, Janina" uniqKey="Geiler J" first="Janina" last="Geiler">Janina Geiler</name></author><author><name sortKey="Klassert, Denise" sort="Klassert, Denise" uniqKey="Klassert D" first="Denise" last="Klassert">Denise Klassert</name></author><author><name sortKey="Doerr, Hans Wilhelm" sort="Doerr, Hans Wilhelm" uniqKey="Doerr H" first="Hans Wilhelm" last="Doerr">Hans Wilhelm Doerr</name></author><author><name sortKey="Cinatl, Jindrich" sort="Cinatl, Jindrich" uniqKey="Cinatl J" first="Jindrich" last="Cinatl">Jindrich Cinatl</name></author></analytic><series><title level="j">Investigative ophthalmology & visual science</title><idno type="eISSN">1552-5783</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiviral Agents (pharmacology)</term><term>Apoptosis</term><term>Caspase 3 (metabolism)</term><term>Cells, Cultured</term><term>Chemokines (metabolism)</term><term>Cytopathogenic Effect, Viral</term><term>Dose-Response Relationship, Drug</term><term>Humans</term><term>Influenza A Virus, H1N1 Subtype (physiology)</term><term>Influenza A Virus, H2N2 Subtype (physiology)</term><term>Influenza A Virus, H5N1 Subtype (physiology)</term><term>Interferon Type I (pharmacology)</term><term>Interferon-gamma (pharmacology)</term><term>RNA, Messenger (metabolism)</term><term>Retinal Pigment Epithelium (pathology)</term><term>Retinal Pigment Epithelium (virology)</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>Ribavirin (pharmacology)</term><term>Virus Replication (drug effects)</term><term>Virus Replication 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xml:lang="fr"><term>Apoptose</term><term>Cellules cultivées</term><term>Effet cytopathogène viral</term><term>Humains</term><term>RT-PCR</term><term>Relation dose-effet des médicaments</term><term>Réplication virale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Ocular involvement in influenza A virus diseases is common but usually limited to mild conjunctivitis. Rarely, inflammation of the choriocapillaris may result in atrophia of the retinal pigment epithelium (RPE). Primary human retinal pigment epithelial (RPE) cells were infected with seasonal (H1N1 A/New Caledonia/20/99, H3N2 A/California/7/2004) or highly pathogenic avian H5N1 (A/Thailand/1(Kan-1)/04, A/Vietnam/1203/04, A/Vietnam/1194/04) influenza strains.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country></list><tree><noCountry><name sortKey="Cinatl, Jindrich" sort="Cinatl, Jindrich" uniqKey="Cinatl J" first="Jindrich" last="Cinatl">Jindrich Cinatl</name><name sortKey="Doerr, Hans Wilhelm" sort="Doerr, Hans Wilhelm" uniqKey="Doerr H" first="Hans Wilhelm" last="Doerr">Hans Wilhelm Doerr</name><name sortKey="Geiler, Janina" sort="Geiler, Janina" uniqKey="Geiler J" first="Janina" last="Geiler">Janina Geiler</name><name sortKey="Klassert, Denise" sort="Klassert, Denise" uniqKey="Klassert D" first="Denise" last="Klassert">Denise Klassert</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Michaelis, Martin" sort="Michaelis, Martin" uniqKey="Michaelis M" first="Martin" last="Michaelis">Martin Michaelis</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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